Remember the ABCDEFG of Corynbacterium Diptheriae:
ADP-ribosylation of EF-2 is the mechanism of action
Beta-prophage encodes exotoxin
Corynebacterium
Diphtheriae
Exotoin acts by inhibiting protein synthesis via ADP ribosylation of Elongation Factor 2
Granules (Lab diagnosis: gram-positive rods with metachromatic Granules)
Thursday, February 11, 2010
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