Dapsone

Mechanism of action is by inhibiting the synthesis of Dihydrofolic acid

Dosage of DapsONE is 100 mg/day - ONE hundreD mg per Day

Treatment of Dermatitis herpetiformis = Dapsone

Dapsone is used to treat many Dermatological conditions (A to Z : Acne, Behcets, Kaposi's Sarcoma, Lupus erythematosus, Leprosy, Mycetoma, Pemphigus, Pyoderma gangrenosum, Rhinosporidiosis, spider bites etc etc !!!)

Side effects of Dapsone : blooD ( methemoglobinemia, hemolysis and anemia), Dapsone hypersensitivity syndrome ( Mainly Dermatological manifestations - Mononucleosis like rash, skin eruptions, etc), Hepatotoxity etc.

Basal & Squamous cell Carcinoma

BAsal cell carcinoma is also called RODent ulcer and arises from Pylosebacious Adnexia {Remember BARODA & BAPA}.

Squamous cell carcinoma arises from the Prickle cell layer of Malphigian layer of skin {Remember: SPM - Social and Preventive Medicine}

Drugs causing photosensitivity

Remember Photosensitivity causing drugs are PQRST:

Phenothiazine, Psoralen,

Quinines,

Retinoids,

Sulphonamides,

Tetracyclines, Thiazines