Monday, December 7, 2009

Treatment of Leprosy

For Paucibacillary Leprosy -
  • Daily - Dapsone 100 mg 
  • Monthly - Rifampicin  600 mg
  • Duration: 6 months 
For Multibacillary Leprosy -
  • Daily - Dapsone 100 mg + Clofazamine 50 mg
  • Monthly - Rifampicin 600 mg + Clofazamine 300 mg
  • Duration: 2 yrs 
Remember this with the formula D / R for paucibacillary and DC / RC for multibacillary 
Explanation: The denominator is the monthly drug to be taken. In case of multibacillary leprosy, note that the dose of Clofazamine, be it monthly or daily, is half the dose of other drug taken along with it ( 100 / 2 = 50, 600 / 2 = 300 ). Duration of treatment is 1/2 yrs and 2 yrs for Pauci & Multibacillary leprosy respectively.

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